| Pair Name | Rutin, Orlistat | ||
| Phytochemical Name | Rutin (PubChem CID: 5280805 ) | ||
| Anticancer drug Name | Orlistat (PubChem CID: 3034010 ) | ||
| Structure of Phytochemical |
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2D
MOL
3D
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| Structure of Anticancer Drug |
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| Pair Name | Rutin, Orlistat | |||
| Disease Info | [ICD-11: 2C60] | Breast cancer | Investigative | |
| Biological Phenomena | Induction-->Apoptosis | |||
| Gene Regulation | Down-regulation | Expression | FAS | hsa355 |
| Up-regulation | Expression | GSS | hsa2937 | |
| In Vitro Model | MCF-7 | Invasive breast carcinoma of no special type | Homo sapiens (Human) | CVCL_0031 |
| PANC-1 | Pancreatic ductal adenocarcinoma | Homo sapiens (Human) | CVCL_0480 | |
| Result | Rutin and orlistat produce antitumor effects via antioxidant and apoptotic actions | |||
| No. | Title | Href |
|---|---|---|
| 1 | Rutin and orlistat produce antitumor effects via antioxidant and apoptotic actions. Naunyn Schmiedebergs Arch Pharmacol. 2019 Feb;392(2):165-175. doi: 10.1007/s00210-018-1579-0. | Click |
